This design studies the precision positioning principle and structure composition of 4D Micro motion stage. Which is a highly precision positioning instrument. It can realize three directions’ regulation, including X, Y and Z. by the motor driving of wheel gear, gear rack and threads. And it can also realize level angle and angle of elevation’s driving .It is mainly used in engineering experiment. As the poisoning control stent it is used to poisoning control of various optical instrument. This devise can be installed on a long guide way to measure a long distance. To realize highly precision poisoning’s fast location, in this design I adopt the way of coarse adjustment trimming combine together. After finish the design I know more about the device’s system constitution and work principle and most important what I designed can satisfy the require precision. Realize the task target requirement that the coarse adjustment coverage of X is 0~25mm, resolution rate is 0.001 mm , the coverage of Y is ±25mm, resolution rate is 0.1mm, the coverage of Z is 0~22mm , the coarse adjustment coverage of deflection angle is 0~360°, the trimming coverage is±5°